Ganglion cysts are a benign bulge or lump that appear most often around the hand/wrist or foot. They are usually an accumulation of fluid from nearby joints or tendons. Cysts can also be painful. Ganglion Cysts usually appears without any particular cause and can affect anyone. Many cysts can disappear without treatment (38-58% of cases) but if the cyst is interfering with your hand or wrist function, the therapist can help create a treatment plan to maintain range of motion, strength, and reduce scar tissue around the affected area to reduce symptoms.